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Filtered Search Results
Medchemexpress LLC TL-895 | 1415823-49-2 | 99.9% | 447.50 | 50 MG
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TL-895 is a potent, orally active, ATP-competitive, and highly selective irreversible BTK inhibitor. It shows activity against recombinant BTK and effectively inhibits the production of inflammatory factors. This compound is used in studies of chronic lymphocytic leukemia (CLL), myelofibrosis (MF), and B-cell malignancies.
- Potent, orally active, ATP-competitive, and highly selective irreversible BTK inhibitor
- Inhibits recombinant BTK (average IC50: 1.5 nM)
- Inhibits BLK, BMX, and TXK kinases
- Inhibits BTK auto-phosphorylation at the Y223 site (IC50: 1-10 nM)
- Effectively inhibits the production of inflammatory factors including IL-8, IL-1β, MCP-1, and TNF-α
- Reduces chemotactic migration of myelofibrosis cells towards SDF-1
- Used for studies of chronic lymphocytic leukemia, myelofibrosis, and B-cell malignancies
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eMolecules Ambeed / 5-Methoxy-2-nitrobenzaldehyde / 250mg / 521413059 / A166000 / / 20357-24-8 / MFCD00456498 / 181.147 / C8H7NO4
Ambeed / 5-Methoxy-2-nitrobenzaldehyde / 250mg / 521413059 / A166000 / / 20357-24-8 / MFCD00456498 / 181.147 / C8H7NO4
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eMolecules Ambeed / 1-Ethyl-1H-indole-5-carbaldehyde / 250mg / 600846262 / A714518 / / 944893-74-7 / MFCD09455244 / 173.215 / C11H11NO
Ambeed / 1-Ethyl-1H-indole-5-carbaldehyde / 250mg / 600846262 / A714518 / / 944893-74-7 / MFCD09455244 / 173.215 / C11H11NO
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eMolecules Ambeed / 555-((135-Triazine-246-triyl)tris(azanediyl))triisophthalic acid / 100mg / 633658352 / A555996 / / 776242-98-9 / [null] / 618.471 / C27H18N6O12
Ambeed / 555-((135-Triazine-246-triyl)tris(azanediyl))triisophthalic acid / 100mg / 633658352 / A555996 / / 776242-98-9 / [null] / 618.471 / C27H18N6O12
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eMolecules Ambeed / 35-Dimethylisoxazole-4-carbonyl chloride / 1g / 625594467 / A718537 / / 31301-45-8 / MFCD00052555 / 159.570 / C6H6ClNO2
Ambeed / 35-Dimethylisoxazole-4-carbonyl chloride / 1g / 625594467 / A718537 / / 31301-45-8 / MFCD00052555 / 159.570 / C6H6ClNO2
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eMolecules Ambeed / 2-((23-Dimethylphenyl)amino)benzoic acid / 5g / 552573668 / A138400 / / 61-68-7 / MFCD00051721 / 241.290 / C15H15NO2
Ambeed / 2-((23-Dimethylphenyl)amino)benzoic acid / 5g / 552573668 / A138400 / / 61-68-7 / MFCD00051721 / 241.290 / C15H15NO2
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eMolecules Ambeed / 4-Hydroxy-35-dimethylbenzaldehyde / 5g / 552573567 / A138338 / / 2233-18-3 / MFCD00006946 / 150.177 / C9H10O2
Ambeed / 4-Hydroxy-35-dimethylbenzaldehyde / 5g / 552573567 / A138338 / / 2233-18-3 / MFCD00006946 / 150.177 / C9H10O2
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Medchemexpress LLC UNC10217938A | 1347749-97-6 | 99.75% | 456.54 | 50 MG
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UNC10217938A is a 3-deazapteridine analog with strong oligonucleotide enhancing effects. It enhances oligonucleotides effects by modulating their intracellular trafficking and release from endosomes, and also enhances the effects of antisense and siRNA oligonucleotides.
- 3-deazapteridine analog with strong oligonucleotide enhancing effects.
- Enhances oligonucleotide effects by modulating intracellular trafficking and release from endosomes.
- Enhances the effects of antisense and siRNA oligonucleotides.
- Strongly enhances luciferase induction in HelaLuc705 cells.
- Can substantially enhance effects of receptor targeted oligonucleotide conjugates.
- Can enhance effects of uncharged morpholino oligonucleotides as well as negatively charged oligonucleotides.
- Causes partial release of oligonucleotide from late endosomes to the cytosol followed by nuclear accumulation.
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ACCUSTANDARD INC DIBUTYLCHLORENDATE 1ML
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NC3728466 DIBUTYLCHLORENDATE 1ML
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eMolecules Ambeed / 5-Methylthiazole-2-carboxylic acid / 250mg / 524990445 / A104189 / / 61291-21-2 / MFCD08060736 / 143.160 / C5H5NO2S
Ambeed / 5-Methylthiazole-2-carboxylic acid / 250mg / 524990445 / A104189 / / 61291-21-2 / MFCD08060736 / 143.160 / C5H5NO2S
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Medchemexpress LLC S65487 (VOB560) | 1644600-79-2 | 99.9% | 717.26 | 50 MG
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S65487 (VOB560) is a potent and selective BCL-2 inhibitor and a proagent of S55746. It is active against BCL-2 mutations such as G101V and D103Y, and exhibits poor affinity with MCL-1, BFL-1, and BCL-XL. This compound induces apoptosis and demonstrates anticancer activities.
- Potent and selective BCL-2 inhibitor
- Active against BCL-2 mutations (G101V and D103Y)
- Induces apoptosis and inhibits cell proliferation in various hematological cancer cell lines
- Demonstrates anticancer activities in vivo, causing complete tumor regression
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eMolecules Ambeed / (2-Chlorophenyl)diphenylphosphine / 100mg / 599117945 / A1352609 / / 35035-62-2 / [null] / 296.730 / C18H14ClP
Ambeed / (2-Chlorophenyl)diphenylphosphine / 100mg / 599117945 / A1352609 / / 35035-62-2 / [null] / 296.730 / C18H14ClP
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eMolecules JW PharmLab LLC / (6-Aza-spiro[2.5]oct-1-yl)-carbamic acid benzyl ester / 500mg / 456109109 / 60R0793 / 98.000 / 1239852-33-5 / MFCD20278310 / 260.337 / C15H20N2O2
JW PharmLab LLC / (6-Aza-spiro[2.5]oct-1-yl)-carbamic acid benzyl ester / 500mg / 456109109 / 60R0793 / 98.000 / 1239852-33-5 / MFCD20278310 / 260.337 / C15H20N2O2
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eMolecules Ambeed / 6-Iodonicotinic acid / 1g / 572987042 / A693349 / / 13054-02-9 / MFCD03426924 / 249.007 / C6H4INO2
Ambeed / 6-Iodonicotinic acid / 1g / 572987042 / A693349 / / 13054-02-9 / MFCD03426924 / 249.007 / C6H4INO2
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Methy-d3 (toluenesulfonate) | 7575-93-1 | MFCD00069406 | 99.8% | 189.25 g·mol⁻¹ | C8H7D3O3S | 50mg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Methy-d3 (toluenesulfonate) is the deuterium labeled Methy toluenesulfonate[1]
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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